This comprehensive review of the literature is based on the analysis and research carried out on autism spectrum disorder (ASD), a brain development disorder characterized by difficulties in social interaction, verbal and non-verbal communication and repetitive behaviors. . Social problems include less attention to social stimuli, less eye contact, and learning difficulties. The communication problem is caused by a significant delay in language development because it affects information processing in the brain by changing the way nerve cells and their synapses connect and organize. Because the symptoms characterized by each affected individual are unique, they are called “spectrum disorders.” This comprehensive review of the literature covers topics involving neighborhood deprivation, stress, behavior, quality of life of individuals with autism and their families, and biological factors. factors involved in the autistic group. There is no cure for autism, but research ideas and article summaries are included with the aim of supplementing knowledge about autism. Neurological connections have also been made to understand the complex nature of this disorder.2. BACKGROUND It was Eugen Bleuler who coined the word “autism” in egocentric schizophrenic patients. The beginnings of autism analysis began as early as 1939 as an extension of psychoanalysis, a method developed by Sigmund Freud. Psychoanalysis has been mainly used in the therapeutic treatment of psychological disorders and has thus extended to autism, which is also characterized by brain disorders. Leo Kanner, a psychiatrist at John Hopkins University was the first to establish the term "early childhood autism" which he described as a distinct neurological disease...... middle of article.... .. had a brain volume 6% greater than that of the others. who was not autistic. Latefa A. Dardas and Muayyad M. Ahmad from the University of Jordan discussed at length the quality of life (QoL) of parents of children with autistic disorder. The objectives of this study were: (1) to examine differences in quality of life between fathers and mothers of children with autistic disorders in a sample from an Arab country, and (2) to examine the psychosocial correlates of quality life of children with autistic disorders. Arab parents of children with autistic disorders. The results showed no significant differences in the physical, psychological, social and environmental health of fathers and mothers of children with autistic disorders. Additionally, both parents showed nearly similar bivariate correlations between reported QoL levels and their parenting stress, coping strategies, and demographic characteristics...