The greater number of gene cluster sets in vertebrates, compared to flies, demonstrates the reason why vertebrates are higher organisms. And although they function similarly, it is somite signaling in vertebrates, rather than just signaling from fly body segments, that sets them apart. It is also interesting to see how evolutionary adaptations have resulted in or been the cause of the loss of specific gene sequences encoding the development of body parts that are no longer necessary for specific organisms, such as the loss of certain fingers in amphibians. . Understanding the conservation of these genes allows for more meaningful uses of certain organisms in research and may ultimately help understand the evolutionary history of these organisms, relative to each.