IntroductionThe incidence of type 2 diabetes is increasing rapidly. There were approximately 2.4 million people with type 2 diabetes in Canada in 2008–2009 (Public Health Agency of Canada [PHAC], 2011), and 5 million Canadians over the age of 20 had prediabetes in 2004 ( PHAC, 2011). It is this group with prediabetes that this article will focus on. Prediabetes was defined by the American Diabetes Association as blood sugar levels above normal but not meeting diagnostic criteria for diabetes (The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. American Diabetic Association, 2003). Although the World Health Organization (World Health Organization [WHO], 2006) uses different thresholds for impaired fasting glucose (IFG) and impaired glucose tolerance (IGT), the definition remains the same. This is because prediabetes is the condition that lies between normal values ​​and those that meet the criteria for a diagnosis of diabetes. Although these two definitions differ in some aspects, there is a general consensus (Lindstrom et al., 2006; Norris et al., 2005; Pan et al., 1997) that it is at this stage of the disease that type 2 diabetes can be reversed. . Several studies have demonstrated the reversal of a prediabetic state to a normoglycemic state (Norris et al., 2005). This prediabetic state can precede type 2 diabetes itself by several years. This is where we can focus our attention and efforts to stem the tide of diabetes. This prediabetic state has been shown to be responsive to several interventions: exercise and diet as well as pharmacological measures. The key among these various interventions is the control of the hyperglycemic state and the increased sensitization of cells to glucose and pr...... middle of article ......oi: 10.1172/JCI29069Statistics Canada. (2005). Projections of Aboriginal populations, Canada, provinces and territories (91-547-XWE). Washington, DC: US ​​Government Printing Office. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. American Diabetes Association. (2003). Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care, 26, 3160-3167. doi: 10.2337/diacare.26.11.3160 ​​World Health Organization. (1965). Diabetes mellitus: report of a WHO expert committee (technical report 310). Retrieved from: http://whqlibdoc.who.int/trs/WHO_TRS_310.pdfWorld Health Organization. (2006). Definition and diagnosis of diabetes mellitus and intermediate hyperglycemia (report of a WHO/FID consultation). Retrieved from the World Health Organization website: http://www.idf.org/webdata/docs/WHO_IDF_definition_diagnosis_of_diabetes.pdf