Osteoarthritis (OA), which is a chronic progressive degenerative disease, can cause joint stiffness, swelling, pain and loss of mobility, characterized by inflammation of the cartilage and the synovium. A high prevalence of osteoarthritis is observed mainly in the elderly population (85% of people over 65 years old worldwide). Although there is no chance of complete cure of osteoarthritis, the primary management of osteoarthritis relies on prescribing analgesics and nonsteroidal anti-inflammatory drugs (NSAIDs) to reduce symptoms ( pain, stiffness, etc.). But prolonged use of pharmacological agents leads to significant gastrointestinal, renal and cardiovascular side effects. So, as alternative therapies, nutraceuticals and supplements are on the rise. Say no to plagiarism. Get a tailor-made essay on “Why violent video games should not be banned”? Get the original essay The term “nutraceutical” was developed from “nutrition” and “pharmaceutical” in 1989 by DeFelice and was initially defined as “a food (or part of a food) that provides medical or health benefits, including the prevention and/or treatment of disease.” Some of the most commonly used nutraceuticals in joint pathologies include glucosamine, chondroitin sulfate, hyaluronic acid, krill oil, fish oil, turmeric, gamma-linolenic acid, and unsaponifiables. avocado and soy. Recent studies indicate that other natural compounds like phytoflavonoids, polyphenols and bioflavonoids, found in fruits, teas, spices, wine and vegetables, have shown the greatest potential to modify disease and symptoms osteoarthritis due to their anti-inflammatory and anti-catabolic actions and their protective effects against oxidative stress. : This is just a sample. Get a personalized article from our expert editors now. Get a personalized essay Nutraceuticals are well proven to improve cartilage health, but preclinical studies are still needed to analyze the activity of nutraceutical products. As a result, nutraceuticals have been extensively studied in in vivo efficacy studies that have demonstrated significant anti-inflammatory activity in both acute and chronic inflammation. The objective of the review is to briefly discuss commonly used neutracetics, including their role in osteoarthritis, as well as the preclinical studies performed to prove the effectiveness of these agents...