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Essay / Suzie's Analysis - 1349
Aspirin binds to COX-2, a protein that makes prostaglandins, thereby inhibiting its function. Prostaglandins are normally released from damaged tissue at Dave's sprained ankle, stimulating nerve endings to produce a sensation of pain (Martini, p. 46). Aspirin is also known as an anticoagulant because it inhibits the production of prostaglandins which also form platelets, used for blood clotting. This is why people who are prone to heart attacks take aspirin to reduce the risk of blood clots. (Hoffman, 2011)B. Fainting1. Why did Suzie faint when she got up from the table? Explain the specific changes in her CVS that caused her to pass out. There are few reasons that contributed to Suzie's fainting. Skeletal muscle helps propel blood through veins toward the heart. Suzie suffers from hypotension mainly because she is starving. Without nutrients from the small intestine, the body is forced to use stored fats and proteins. The cold environment of the kitchen further lowered his blood pressure. As a homeostatic mechanism, blood vessels contract to keep Suzie and vital organs warm. The lack of oxygen delivered to the brain caused Suzie to faint and temporarily lose consciousness (Martini, p. 722). Another reason Suzie fainted was her prolonged QT interval, detailing the time of ventricular depolarization/repolarization of her heart by Purkinje fibers. Third, Suzie's development of anemia contributed to her fainting because there likely weren't enough healthy red blood cells to supply oxygen to her brain. When Suzie collapsed, she lay down in a horizontal position, increasing the supply of blood and oxygen to the brain. (Martini, p. 722)C. Ectopic Hear...... middle of article ......als.org/content/94/6/2129.full· Hoffman, Lucas, MD, PhD. “Aspirin 101” 2011. http://health.howstuffworks.com/medicine/medication/aspirin3.htm · Lacroix, Pierre. An overview of QT interval assessment in safety pharmacology. Figure 10.7.1. Current protocols in pharmacology. July 2006 · Martini, Frederic C. Fundamentals of anatomy and physiology. 7th ed. Pearson. · National Heart, Lung, and Blood Institute. "Explore long QT syndrome". September 2011. http://www.nhlbi.nih.gov/health/health-topics/topics/qt/· Pritts, Sarah D., MD. University of Cincinnati School of Medicine. Diagnosis of eating disorders in primary care. January 15, 2003. http://www.aafp.org/afp/2003/0115/p297.html· Yanowitz, Frank G., MD. The ECG Learning Center at the Alan E. Lindsay Center. The University of Utah School of Medicine. 2006 http://library.med.utah.edu/kw/ecg/ecg_outline/Lesson12/index.html