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Essay / Lymphoma Essay - 1327
LYMPHOMAIntroductionLymphoma refers to a form of blood cancer resulting from more rapid than normal division of T or B lymphocytes; this condition also occurs when these cells live longer than normal (Pace, Cassio & Glass, 2007). The organs in which the disease can develop include the spleen, lymph nodes, bone marrow, among others. Ideally, this disease is the presentation of a solid tumor of lymphoid cells. Treatment for the disease could involve chemotherapy, radiotherapy and bone marrow transplantation. Scientists say the disease can be cured and cure depends on factors such as its stage, histology and type. The malignant cells originate in the lymph nodes and resemble enlargement of the lymph node. There are also extranodal sites of origin, including the skin, bone, intestines, tonsils, and brain. There is a close relationship between lymphomas and lymphoid leukemias whose sites of origin are also lymphocytes; however, leukemias do not involve static tumors but the bone marrow and circulating blood (Pace, Cassio & Glass, 2007). ContextThe first description of lymphoma dates from 1832, by Thomas Hodgkin, hence its name lymphoma of Hodgkin. In subsequent years, scientists described other types of diseases, as well as various classifications. A working formulation, dating from 1982, gained immense popularity because it developed the category of non-Hodgkin lymphomas constituting 16 diseases. Physicians, however, are abandoning the NHL label, believing it to have limited utility because its 16 diseases have negligible similarities (Ansell, 2006). In 2008, the WHO proposed a further classification criterion for 70 types of lymphoma. Biology of Hodgkin's Lym disease...... middle of article ......observed in individuals over 60 years old. Lymphoma prevalence also varies by race; for example, in the United States, the frequency of the disease is higher among Whites than among Asians and African Americans (Gobbi et al, 2013). ConclusionLymphoma is a form of cancer that affects the lymphatic system, with most cases occurring in developed countries. The disease is characterized by various observable symptoms such as enlarged lymph nodes, weight loss, night sweats and fever. Diagnosing the disease involves tests such as physical exams, x-rays, biopsies and blood tests. Treatment involves targeted therapy, chemotherapy, biological therapy, radiotherapy and vigilant development. Besides the pathology of the infection, individuals may also experience other complications during their lifetime, including immune system suppression, infertility, and stem cell transplantation...