SUMMATIVE EVALUATIONQuestion 1.1. Symmetrical bilateral sensorineural hearing loss with normal to moderate slope2. This is otoxicity, the site of the lesion is located within the inner ear in the hair cells of the cochlea. Mr. T is currently taking medications for multidrug-resistant tuberculosis, many anti-tuberculosis medications are ototoxic (side effect of hearing loss and/or tinnitus) to hearing (Cristobal & Oghalai, 2008; Da Costa, Rosito & Dornelles , 2009; Munro & Blount, 2009; The drug for multidrug-resistant tuberculosis is ototoxic and therefore causes functional impairment and cell generation in the tissues of the inner ear, and particularly in the end organs and neurons of the cochlear and vestibular divisions of the cranial nerve eight (Munro and Blount , 2009). ; Schreiber, Agrup, Haskard and Luxon, 2010). Damage to these structures affects the hearing system and balance, leading to hearing loss, tinnitus (ringing in the ears), and dizziness (Cristobal & Oghalai, 2008; Da Costa, Rosito & Dornelles, 2009; Munro & Blount, 2009; The medicine contains aminoglycoside compounds; amoniglycosides cause loss of hair cells in the corti (Cristobal & Oghalai, 2008; Da Costa, Rosito & Dornelles, 2009; Munro & Blount, 2009; Schreiber, Agrup, Haskard & Luxon, 2010). When it is most severe, it is the basal tower of the cochlea which gradually diminishes towards the apex. The inner row of outer hair cells is affected, followed by the outer row, then later by the rest of the organ (Cristobal & Oghalai, 2008; Da Costa, Rosito & Dornelles, 2009; Munro & Blount, 2009; Schreiber, Agrup, Haskard and Luxon, 2010).3. it is necessary to prescribe/recommend to the patient a medication which is the...... middle of paper ....... P. (2010). Broadband acoustic reflex testing in a test battery to predict middle ear dysfunction. Hearing Research, 263(1), 52-65.Munro, K.J., & Blount, J. (2009). Adaptive plasticity in the brainstem of adult listeners following earplug-induced deprivation. The Journal of the Acoustical Society of America, 126(2), 568-571. Schreiber, BE, Agrup, C., Haskard, DO and Luxon, LM (2010). Sudden sensorineural hearing loss. The Lancet, 375(9721), 1203-1211. Sliwinska-Kowalska, M. and Davis, A. (2012). Noise-induced hearing loss. Noise and Health, 14(61).Thorne, PR, Ameratunga, SN, Stewart, J., Reid, N., Williams, W., Purdy, SC, ... and Wallaart, J. (2008). Epidemiology of noise-induced hearing loss in New Zealand. NZ Med J, 121. (Cristobal & Oghalai, 2008; Da Costa, Rosito & Dornelles, 2009; Munro & Blount, 2009; Schreiber, Agrup, Haskard & Luxon, 2010)