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  • Essay / Cutaneous lupus research

    Table of contentsExperimentObjectivesMethods and materialsPossible resultsConclusionCutaneous lupus is a condition caused by the body's poor reaction to UV light and all types of radiation. It is an autoimmune disease that affects the body's ability to recognize foreign invaders in its own tissues, resulting in skin damage. However, the body normally protects itself from foreign invaders like bacteria and viruses; in this case, the body mistakenly attacks healthy tissues and organs. As a result, this disease could lead to health problems in which the disease not only affects the skin but can also affect other bodily organs such as the kidneys, blood vessels, and the nervous system. There are different types of lupus, the most common type being systematic lupus erythematosus (SLE), but cutaneous lupus erythematosus (CLE) is the form that only affects the skin and is very common in people from different regions of the world. A person can live their entire life without CLE becoming SLE, a type of lupus that spreads to different bodily organs such as the brain, kidneys, lungs, and arteries. Say no to plagiarism. Get a tailor-made essay on “Why Violent Video Games Should Not Be Banned”? Get the original essay Cutaneous lupus is a disease that affects all age groups, ethnicities, and genders. People with CLE will notice a sunburn on their face, usually butterfly-shaped. Butterfly rash is a sign of acute cutaneous lupus (ACLE). The rash invades the bridge of the nose and creates a wing-like shape around the cheeks. This rash can also appear on other parts of the body. The first symptom of cutaneous lupus is a rash that can spread to other organs. Lesions caused by cutaneous lupus are usually red, scaly, and thick, but tend to be painless and not itchy. Additionally, lesions that persist for a long time can eventually become cancerous. Subacute cutaneous lupus appears as ring-shaped lesions, mainly on parts of the body exposed to solar radiation, such as the arms, neck, shoulders and face. These lesions are not itchy or flaky, although they tend to have discolored pink pigment. As the lesions are photosensitive, it is important to avoid too much exterior radiation or fluorescent lamps indoors. Additionally, a person can consider using certain home remedies such as turmeric-based masks, which help in healing the lesions. Many medications have been used to try to treat this condition, but not all individuals experience the same results. For example, corticosteroids are toxic to some people, mainly children. Therefore, when dealing with children with lupus, it is crucial to experiment with home remedies rather than harmful steroids. However, in adults, the most commonly used treatment methods currently are topical ointments, including steroid creams or gels, for which, if not used as directed, inadequate treatment can result in permanent scarring. . When diagnosing cutaneous lupus, the identification of this condition is not accurate. As a result, scientists take a living sample called a biopsy and compare it to that of patients with the disease in order to conclude that the individual does indeed have lupus. So, diagnosing this disease by comparing images in a laboratory means an error ofpossible diagnosis. Additionally, this disease is nicknamed “the great imitator” due to its vague symptoms. So, prescribing strong medications without a better way to diagnose the disease is dangerous. There is therefore a need for new alternative treatments using immunomodulators, a new class of drugs. These new treatment options aim to minimize the side effects caused by corticosteroids. Lupus can be prevented through proper patient education about the effects of heat and sun on the skin. Patients should also be informed of the need to avoid drug use. Skin lesions resulting from cutaneous lupus should also not be handled as this can encourage the formation of new lesions on the surface of the skin. The use of harmless makeup products to conceal lesions is recommended, but should not be applied to broken skin. The best preventive treatment is to avoid harmful radiation, experiment with home remedies like turmeric face masks, and use sunscreens to protect against radiation exposure. For people allergic to sunscreen, it is helpful to wear wide-brimmed hats to help shade the entire face so that even without sunscreen, the face is protected. Patients should also avoid sunbathing, traveling to destinations near the equator, and tanning their skin. Cutaneous lupus can be treated either with prescription medications such as corticosteroids, calcineurin inhibitors, steroids, or with alternative herbal medications. Physical treatments such as cryosurgery, laser ablation, and skin abrasion have also been shown to be effective. The advantage of using this treatment is that it is however easily available; it can get very expensive. Currently, no drugs have been approved for the treatment of cutaneous lupus, which is a limitation in the therapeutic approach. Most drugs currently used are part of a regimen aimed at treating the underlying cause of the disease, an aspect of great interest to scientists. They include topical corticosteroids, for example methylprednisolone (used on the face and head), triamcinolone acetonide, betamethasone valerate (used on the back, stomach and extremities) and clobetasol (used on the palmar surface and the plantar surface of the hands and feet). ; Calcineurin inhibitors such as tacrolimus and pimecrolimus have also been used and salbutamol has shown some success in treating cutaneous lupus.ExperienceThe following section discusses what my proposed study will examine.ObjectivesGeneral objectiveEstablish the effectiveness of treatments alternatives and medications prescribed for cutaneous lupus in any season of the year. Specific Objectives Determine the development of resistance to prescription lupus medications during various seasons of the year. Establish the lupus response cutaneous to various medications that may be offered.To establish alternative medications to prescription medications for cutaneous lupus to determine their effectiveness.Methods and MaterialsTo achieve the objective of this study, this research will be conducted for a duration of 1 year and will include 100 participants with cutaneous lupus who will be selected from a wide range of ethnicities. Notably, no specific race or gender is specified. To determine the development of lupus prescription resistance during different seasons of the year, study participants will be divided into two groups randomly, Group A and Group B. For..