Some studies have shown that Polysorbate 80 has been linked to infertility in mice, an increased risk of blood clots, heart attack, stroke, heart failure, and even of cancer recurrence. This additive was indicated in a PubMed article as the causative agent of anaphylactic shock in pregnant women. Other studies have shown that this emulsifier is particularly harmful to people with Crohn's disease, whose symptoms include abdominal pain, sometimes bloody diarrhea, and weight loss. Say no to plagiarism. Get a custom essay on “Why Violent Video Games Should Not Be Banned”?Get the original essay Biomedical science researchers, led by Georgia State University, found that Polysorbate 80 disrupted gut flora and created a multitude of unhealthy side effects. This appears to lead to an increase in digestive disorders such as ulcerative colitis, Crohn's disease, and inflammatory bowel disease. Since this emulsifier was introduced, the incidence of metabolic syndrome and other types of obesity-related health problems that lead to heart disease, liver disease, and diabetes have also increased. In one study, scientists fed mice two of the most popular emulsifiers, Polysorbate 80 and Carboxymethylcellulose, at doses high enough to mimic average human consumption. All of the mice showed dramatic changes in their intestines, including increased levels of inflammation. Because their intestinal flora had been adjusted, chronic colitis developed and their immune system responses were damaged. These mice also generated metabolic syndrome, increased food consumption levels, insulin resistance and obesity. Toxicity and carcinogenicity studies were conducted by adding Polysorbate 80 to the diet of groups of B6C3F1 mice and F344/N rats of each sex for 14 days, 13 weeks and 2 years. In this research, groups of five mice and five rats of each sex fed meals containing 0, 3000, 6000, 12500, 25000 or 50000 ppm of Polysorbate 80. In conclusion, under the conditions of these 2-year dietary studies, There was no certain evidence of carcinogenic activity of polysorbate 80 in male F344/N rats based on an increased incidence of pheochromocytomas of the adrenal medulla. The results also showed that there was no presence of carcinogenic activity for polysorbate 80 in female F344/N rats or in male or female B6C3F1 mice. Addition of polysorbate 80 to the diet was associated with fore-stomach ulcers in female mice and with inflammation and squamous hyperplasia of the fore-stomach in both male and female mice...