Genomic conflict occurs when genes affecting the same trait experience different selection pressures because they obey different inheritance rules or undergo opposing selection at different levels of a nested hierarchy. Therefore, genomic conflict can arise in two situations: multilevel hierarchical selection that occurs when one selection process is contained within another selection process, as in the case of meiotic drive and cancer, and a another situation, when transmission is asymmetrical so that the different genetic elements do not follow the same transmission routes. The ancient situation of genomic conflict (asymmetric transmission) can be explained by taking the male sterility of flowering plants such as Plantago coronopis as an example. Plantago coronopis is a gynodioecious rosette plant; that is, it has two types of flowers which consist of flowers which have both male and female parts and other flowers which have only the female parts and greatly reduced sterile male parts or absent. Many species of hermaphrodite plants contain individuals that produce no viable pollen. These male-sterile plants are actually female, unlike normal individuals which have flowers with both male and female reproductive structures. Since mitochondria are passed down only in the female lineage, mitochondrial mutations that improve female fitness are favored by natural selection, regardless of their impact on male fitness. A mitochondrial mutation that reduces male function and improves female function will therefore be selected. However, nuclear genes are transmitted with equal probability through pollen and ovules, and nuclear genes affecting reproductive organs are selected for an equivalent response at the lower level in order to escape the fate of the higher level. response by switching to another “replicator”. Since genomic conflicts decrease fitness at the higher level, such a gene will disappear through selection. However, within a sexual lineage, the sex is capable of combining gemones from different lineages, resulting in the formation of genetic variation within the nuclear genome. It is also capable of creating genetic variation in cytoplasmic genomes and creates opportunities for non-chromosomal genetic elements to switch hosts. Thus, when gamete fusion is followed by meiotic division that produces haploid reproductive cells with genetic recombination and segregation, the genetic elements can associate with replicators different from their original hosts. This therefore shows that sexual organisms are more prone to genomic conflicts than asexual organisms...