Being addicted to drugs, also known as compulsive drug use, even if the drug is not harmful. This problem is described by an inability to stop using a drug; an inability to respect professional, social or family commitments; and sometimes resistance and withdrawal. The latter reflect physical dependence in which the body adapts to the drug, requiring a greater quantity of the drug to accomplish a specific impact (resistance) and evoking drug-specific physical or mental indications if drug use is suddenly stopped (withdrawal). Physical dependence can occur with the constant use of many medications, including many medications prescribed by a doctor, even if taken as directed. Thus, physical dependence does not in itself constitute a constraint, but it is generally accompanied by a habit. This refinement can be difficult to recognize, particularly with prescribed painkillers, for which the need to expand measures may reflect resilience or an escalating fundamental problem, rather than the onset of misuse or of a fixation. (unknown,